Statement 1: Indirect Coombs Test in Pregnancy

This statement is correct. The Indirect Coombs test (ICT) is essential for screening Rh-negative mothers. It detects Rh antibodies in the maternal blood, which are critical for assessing the risk of Rh isoimmunization and subsequent hemolytic disease in the fetus.

Statement 2: Methergin Use During Delivery

This statement is correct. Methergin (Methylergonovine) is an uterotonic medication used to control postpartum hemorrhage. Its administration typically occurs after the delivery of the baby and the placenta, not during the process of delivering the anterior shoulder. Therefore, it is correct that Methergin is withheld at the specific moment of anterior shoulder delivery.

Statement 3: MCA PSV for Fetal Anemia Prediction

This statement is correct. Doppler ultrasonography measuring the Middle Cerebral Artery (MCA) peak systolic velocity (PSV) is a widely accepted, non-invasive method. Elevated MCA PSV indicates increased blood flow velocity, strongly suggesting fetal anemia, often caused by Rh isoimmunization. This helps guide management decisions.

Conclusion on Correct Statements

Based on the analysis, all three statements regarding pregnancy with Rh isoimmunization are correct:

• Statement 1: Indirect Coombs test is performed in the mother.
• Statement 2: Methergin is withheld at delivery of anterior shoulder.
• Statement 3: Middle cerebral artery peak systolic velocity is an accurate method to predict fetal anemia.

Therefore, the correct option includes statements 1, 2, and 3.