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Question

Consider the following statements regarding claudication:
1. It is a marker for silent coronary disease
2. Structured exercise program ( 2 hours per week for 3 months) leads to improvement in symptoms
3. Diabetes mellitus increases the risk and severity of claudication
4. Beta blockers may exacerbate claudication
Which of the above statements are correct?

The correct answer is
1, 2, 3 and 4

Claudication Statements Evaluation

This section evaluates the given statements regarding claudication to determine their accuracy.

Statement 1: Claudication as a Silent Coronary Disease Marker

Correct. Intermittent claudication, often caused by peripheral artery disease (PAD), is strongly associated with atherosclerosis. Patients with PAD frequently have coexisting coronary artery disease (CAD), even without chest pain symptoms. Therefore, claudication can serve as an indicator for underlying silent CAD.

Statement 2: Exercise Program Efficacy

Correct. Structured exercise programs are a primary non-pharmacological treatment for claudication symptoms. Studies show that consistent exercise, such as 2 hours per week for 3 months, significantly improves walking distance and functional capacity in patients with PAD.

Statement 3: Diabetes Mellitus and Claudication

Correct. Diabetes mellitus is a significant risk factor for developing peripheral artery disease. It accelerates atherosclerosis, increasing both the likelihood of experiencing claudication and the severity of the condition.

Statement 4: Beta Blockers and Claudication Exacerbation

Correct. Certain beta blockers, particularly non-selective ones, can potentially worsen claudication symptoms. They may cause peripheral vasoconstriction, reducing blood flow to the limbs and exacerbating pain during exercise.

Conclusion

Based on the analysis, all four statements (1, 2, 3, and 4) are considered correct in the context of claudication.

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Important Questions from Blood Vessels

  1. A 48-year-old smoker presents to the OPD with complaints of cramping pain in both the calves on walking to about 100-150 metres. The pain is relieved on taking rest for about 2-3 minutes and the patient is able to walk for some more distance again before the pain appears. This presentation is suggestive of
  2. Indications for carotid endarterectomy in symptomatic patients are all of the following EXCEPT:
  3. A policeman of 45 years presented with Lipodermatosclerosis over lower medial aspect of left leg, along with a healed venous ulcer. As per the CEAP (Clinical-etiology-anatomy-pathophysiology) classification his clinical classification will be:
  4. Which of the following is NOT a symptom of atherosclerotic occlusive disease at the bifurcation of aorta (Leriche syndrome)?

  5. On second day following femoral embolectomy, the leg is found to be tender, tense and dusky with feeble dorsalis pedis. The most appropriate management would be:
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