The question asks for the largest number that divides $135$ leaving a remainder of $5$, and divides $281$ leaving a remainder of $1$. This means the number we are looking for is the Greatest Common Divisor (GCD) of the numbers obtained after subtracting the remainders from the original numbers.
First, adjust the numbers by subtracting their respective remainders:
The greatest number we need is the GCD of $130$ and $280$.
We find the prime factorization of each adjusted number:
To find the GCD, we take the lowest power of each common prime factor:
Therefore, the GCD is:
$ \text{GCD}(130, 280) = 2^1 \times 5^1 = 10 $
The greatest number that satisfies the conditions is $10$.