Understanding the Reaction of Benzoic Acid and Glycine

The question asks about the product formed when Benzoic acid reacts with Glycine in the presence of the enzyme Acyl synthetase. This is a biochemical reaction involving the conjugation of a carboxylic acid with an amino acid.

The Reaction Process

In the body, many foreign substances or waste products that have a carboxylic acid group are conjugated with amino acids like Glycine to make them more water-soluble and easier to excrete. This process often involves activation of the carboxylic acid.

The enzyme Acyl synthetase facilitates the activation of the carboxylic acid (Benzoic acid in this case). The activated acid then reacts with the amino group of the amino acid (Glycine).

Specifically, the reaction between Benzoic acid and Glycine results in the formation of an amide bond between the carboxyl group of Benzoic acid and the amino group of Glycine. The resulting molecule is called Hippuric acid.

The chemical equation for this reaction can be represented conceptually as:

\(\text{Benzoic Acid} + \text{Glycine} \xrightarrow{\text{Acyl synthetase}} \text{Hippuric Acid} + \text{Water}\)

Analyzing the Options

• N-acetylprocainamide: This is a derivative formed by acetylating the drug procainamide. It is not related to the reaction of Benzoic acid and Glycine.
• Acylic acid: This is a very general term for acids derived from open-chain hydrocarbons. It is not the specific product of this reaction.
• Hippuric acid: This is the N-benzoylglycine. It is the correct product of the conjugation reaction between Benzoic acid and Glycine.
• Salicylic acid: This is 2-hydroxybenzoic acid. It is an isomer of benzoic acid but has a hydroxyl group. It is not formed from Benzoic acid and Glycine reaction.

Therefore, the reaction between Benzoic acid and Glycine in the presence of Acyl synthetase yields Hippuric acid.