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Question

Atrial myxoma is associated with the following except:

The correct answer is
Systolic murmur at apex

To identify the condition associated with atrial myxoma, it's important to understand the clinical manifestations of this condition. Atrial myxoma is a type of primary heart tumor, often found in the atria, and has certain characteristic symptoms and signs due to its mechanical effect within the heart and systemic effects from cytokine production.

  1. Fever and Weight Loss: These are constitutional symptoms often seen in patients with atrial myxomas. They occur due to the release of cytokines like interleukin-6 from the tumor, which can cause systemic inflammation and symptoms similar to chronic infection or malignancy.
  2. Subungual Splinter Haemorrhages: These are small areas of bleeding underneath the fingernails or toenails and can be associated with systemic embolization from parts of the myxoma breaking off and traveling in the bloodstream. This is a known feature of atrial myxoma.
  3. Systolic Murmur at Apex: This is generally not associated with atrial myxoma. Myxomas can cause obstruction of blood flow within the heart, potentially leading to a diastolic murmur, but a systolic murmur at the apex is typically more associated with mitral regurgitation or stenosis due to other causes.

Conclusion: Considering the information above, the feature not typically associated with atrial myxoma is "Systolic murmur at apex." This option is generally more indicative of valvular heart disease rather than a myxoma.

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Important Questions from General Clinical Conditions

  1. The height of the Jugular Venous Pulse is determined by :
  2. The SA node is situated at the junction of:
  3. Reverse splitting of second heart sound is most commonly seen in :
  4. A 70-year-old man with dyspnoea on exertion has been found to have a single second heart sound and a loud diamond-shaped, rough quality systolic murmur best heard at the right $2^{nd}$ intercostal space, radiating to the right carotid artery. Which one of the following is the likely diagnosis ?
  5. Consider the following statements with regard to pulmonary embolism : 

    1. Unexplained breathlessness is the most common symptom. 

    2. When congestive heart failure or pneumonia fail to improve despite standard medical treatment, occult pulmonary embolism should be considered. 

    3. Patients with high clinical likelihood of venous thromboembolism should first undergo D-dimer testing alone without obligatory imaging tests. 

    Which of the statements given above are correct?

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