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Question

An 80-year-old man presents with breathlessness which wakes him up from sleep. His pulse is 90/min and BP is 100/60 mmHg. The examination reveals pedal oedema and basal rales in both lungs. He has dyspnoea on exertion and he has an off and on history of chest pain for the last many years. He has a soft systolic murmur at the apex. This patient may benefit from all of the following except

The correct answer is
Calcium channel blocker

Heart Failure Symptoms Analysis

The patient presents with classic signs and symptoms suggestive of Congestive Heart Failure (CHF):

  • Breathlessness waking from sleep (Paroxysmal Nocturnal Dyspnea)
  • Pedal edema (fluid retention in legs)
  • Basal rales (fluid in lungs)
  • Dyspnoea on exertion
  • History of chest pain (suggestive of underlying coronary artery disease)
  • Soft systolic murmur

The low blood pressure (100/60 mmHg) might indicate compromised cardiac output.

Medication Efficacy in Heart Failure

The question asks which medication is NOT beneficial (an exception) for this patient's likely condition. Standard CHF management aims to relieve symptoms, reduce fluid overload, and improve cardiac function.

Furosemide (Diuretic)

Furosemide is a loop diuretic. It effectively reduces fluid overload by increasing urine output, alleviating symptoms like pedal edema and pulmonary congestion (basal rales, breathlessness). It is beneficial.

ACE Inhibitor

ACE inhibitors (e.g., Ramipril, Enalapril) are cornerstone therapy for CHF. They reduce afterload, decrease preload, and improve cardiac remodeling, leading to symptomatic improvement and increased survival. They are beneficial.

Beta Blocker

Specific beta blockers (e.g., Carvedilol, Bisoprolol, Metoprolol Succinate) are proven to improve outcomes in CHF, especially for patients with reduced ejection fraction. They help by reducing heart rate, contractility, and preventing adverse remodeling. They are beneficial.

Calcium Channel Blocker

Calcium channel blockers (CCBs) are generally not recommended as first-line therapy for heart failure, particularly those with reduced ejection fraction. Non-dihydropyridine CCBs (Verapamil, Diltiazem) can decrease myocardial contractility and worsen heart failure symptoms. Dihydropyridine CCBs (e.g., Amlodipine) may be used for concurrent hypertension or angina but do not directly treat the underlying CHF pathology and can sometimes worsen peripheral edema. Therefore, CCBs are the exception among the given options.

Conclusion on Treatment Exception

Given the clinical presentation of heart failure, Furosemide, ACE inhibitors, and Beta blockers are standard and beneficial treatments. Calcium channel blockers are typically avoided or used with extreme caution in heart failure patients and are therefore the exception.

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Important Questions from Heart Failure

  1. High output cardiac failure is caused by which of the following diseases ? 

    1. Beri-beri 

    2. Severe anaemia 

    3. Thyrotoxicosis 

    Select the correct answer using the code given below:

  2. Kussmaul's sign is present in all of the following conditions, EXCEPT:
  3. Which of the following electro-cardio-graphic findings are manifestations of digitalis intoxication?
    1. Ventricular bigeminy
    2. Ventricular tachycardia
    3. Atrial flutter
    4. Atrial tachycardia with variable block
    Select the correct answer using the code given below:
  4. A 35-year-old labourer worker consulted a local medical practitioner for recurrent attack of chest pain. His elder brother had similar complaint and died at the age of 40 years. The labourer worker was advised to take sublingual nitroglycerin at the time of chest pain. But after taking nitroglycerin, the chest pain increased in intensity. Which one of the following is most likely ?
  5. The treatment of choice for a 32 year old male patient of severe mitral stenosis (Rheumatic) with thickened and calcified valves on echocardiography is:
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