Analysis of Acute Leukaemias EXCEPT Question

The question asks to identify the statement that is NOT true regarding acute leukaemias. Let's evaluate each option:

• Option 1: Promyelocytic leukaemia may present with DIC
  This statement is true. Acute promyelocytic leukaemia (APL), a subtype of AML, is strongly associated with Disseminated Intravascular Coagulation (DIC) due to the release of tissue factor from abnormal promyelocytes.
• Option 2: Gum hypertrophy is a feature of monocytic leukaemia
  This statement is true. Gum hypertrophy or infiltration is a classic clinical sign often seen in acute monocytic leukaemia (AMoL) and other myeloid leukaemias with monocytic differentiation.
• Option 3: Translocation is a common chromosomal abnormality in acute myeloid leukaemia
  This statement is true. Specific chromosomal translocations, such as t(8;21), inv(16), and t(15;17) (in APL), are common and diagnostically important in various subtypes of AML.
• Option 4: Auer rods suggest acute lymphocytic leukaemia
  This statement is false. Auer rods are abnormal, needle-like cytoplasmic inclusions found in the blast cells of patients with Acute Myeloid Leukaemia (AML). They are generally considered absent in Acute Lymphocytic Leukaemia (ALL). Their presence strongly suggests an AML diagnosis.
• Option 5: (Empty)
  This option is not applicable.

Conclusion on Leukaemia Features

Based on the analysis, the only statement that is incorrect is that Auer rods suggest acute lymphocytic leukaemia. Auer rods are a hallmark of acute myeloid leukaemia.

Correct Answer Reasoning: The question requires identifying the exception. Auer rods are characteristic of AML, not ALL. Therefore, the statement linking Auer rods to ALL is false.