A patient with a peptic ulcer is prescribed a proton pump inhibitor and advised to avoid NSAIDs. Which rationale best explains this combined approach?
To promote ulcer healing and prevent further irritation
A proton pump inhibitor (e.g. omeprazole) blocks the H+/K+ ATPase of parietal cells, reducing gastric acid secretion so the ulcer can heal.
NSAIDs inhibit prostaglandins that protect the gastric mucosa (mucus, bicarbonate, blood flow), so avoiding them prevents further mucosal irritation and new ulcers.
Together the two measures promote healing and prevent re-injury. The approach does not aim to increase acid, improve nutrient absorption or prevent dehydration.
Hence, To promote ulcer healing and prevent further irritation.
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Important Questions from Medical-Surgical Nursing
In a patient with a normal temperature and pulse but low blood pressure, which clinical condition should be considered first?
When caring for a patient with hypocalcemia, which symptom should the nurse closely observe?
A post operative patient is receiving dextrose 5% and 0.45 normal saline at 160 ml/hour. The nurse notices puffiness, weight gain of 2 kg and hypotension with complaints of muscle cramps and confusion. The serum sodium level is 126 mEq/L. Which of the following is the most likely cause of these findings?
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A patient arrives with severe burns. After ensuring a patent airway, what is the next step in the emergency management?
