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Question

A patient is admitted with severe diarrhoea and vomiting. On examination, he is hypotensive and dehydrated. His haemoglobin is $19$ gm%. The most likely reason for raised haemoglobin is

The correct answer is
Relative polycythaemia

Understanding Raised Haemoglobin in Dehydration

The patient presents with symptoms of significant fluid loss: severe diarrhoea and vomiting. This leads to dehydration and hypotension (low blood pressure).

Physiological Impact of Dehydration

Dehydration causes a decrease in the plasma volume within the blood. Haemoglobin concentration is measured as the amount of haemoglobin per unit of blood volume.

  • When the plasma volume decreases, the concentration of red blood cells, including haemoglobin, increases relative to the total blood volume.
  • This makes the measured haemoglobin level appear higher than the patient's actual red blood cell mass.

Identifying Relative Polycythaemia

A haemoglobin level of $19$ gm% in this context is most likely due to haemoconcentration caused by dehydration.

  • Relative polycythaemia is characterized by an increase in haemoglobin concentration due solely to a decrease in plasma volume, without an actual increase in red blood cell production.
  • The patient's clinical presentation (hypotension, dehydration) strongly supports this diagnosis.

Differentiating Other Conditions

  • Secondary polycythaemia involves increased red blood cell production due to factors like hypoxia or tumours, which is less likely given the acute symptoms.
  • Polycythaemia vera is a bone marrow disorder causing overproduction of red blood cells, typically presenting more chronically.
  • Essential thrombocythaemia involves increased platelet production, not primarily haemoglobin.

Therefore, the most likely reason for the raised haemoglobin is relative polycythaemia resulting from dehydration.

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Important Questions from General Clinical Conditions

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    2. Narcotic drugs
    3. Iatrogenic-Post RT/Surgery
    4. Hypothyroidism
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    4. More than 10% over 6-12 months
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  3. The ‘Y' descent in JVP waveform represents:
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  5. Regardless of the infectious agent, the most characteristic symptom of infectious esophagitis is:
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