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Question

A 40 year old man with a known case of chronic pancreatitis presents to the OPD with complaint of skin pigmentation over the abdomen. The patient gives a history of chronic use of a hot water bottle to relieve the abdominal discomfort. Which one of the following is the most appropriate diagnosis?

The correct answer is
Erythema ab igne

Understanding the Patient's Condition

The patient is a 40-year-old male diagnosed with chronic pancreatitis. He presents with a specific skin finding: pigmentation over the abdomen. Importantly, he reports a history of regularly using a hot water bottle to manage his abdominal discomfort. This history is crucial for identifying the cause of the skin changes.

Analyzing the Differential Diagnoses

We need to evaluate the given options to determine the most likely diagnosis based on the patient's symptoms and history:

  • Erythema infectiosum: This condition, also known as fifth disease, is caused by the Parvovirus B19. It typically causes a characteristic "slapped cheek" rash on the face, followed by a rash on the limbs. It is not associated with heat exposure or prolonged use of hot water bottles, making it an unlikely diagnosis here.
  • Erythema marginatum: This condition involves transient, migrating, often serpiginous (ring-like or wavy) erythematous (red) skin lesions. It is commonly associated with rheumatic fever. The appearance and cause are different from the described abdominal pigmentation due to heat.
  • Erythema nodosum: This is a form of panniculitis (inflammation of subcutaneous fat) that typically presents as tender, red nodules, most commonly on the shins. It is an inflammatory response and not directly caused by external heat application.
  • Erythema ab igne: This condition is specifically characterized by reticulated (net-like or web-like) reddish-brown pigmentation of the skin. It develops due to prolonged and repeated exposure to moderate heat, such as from hot water bottles, heating pads, or sitting near a fire. The patient's history of chronic hot water bottle use directly aligns with the cause of Erythema ab igne.

Identifying the Most Appropriate Diagnosis

Given the patient's presentation of abdominal skin pigmentation and the clear history of chronic use of a hot water bottle for pain relief, Erythema ab igne is the most fitting diagnosis. The constant application of heat leads to damage to the superficial blood vessels, resulting in the characteristic mottled, reticulated pattern of pigmentation.

Key Factors Supporting Erythema Ab Igne Diagnosis:

  • Skin Pigmentation: The patient has observable skin pigmentation.
  • Location: The pigmentation is on the abdomen, the site where the hot water bottle was applied.
  • Etiology: The patient's history explicitly mentions chronic use of a hot water bottle, a known cause of Erythema ab igne.
  • Appearance: While not explicitly described beyond 'pigmentation', Erythema ab igne typically presents as a reticulated pattern, consistent with chronic heat exposure.

The other options do not fit the clinical picture presented by the patient.

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Important Questions from Miscellaneous

  1. A 42-year old man with history of alcohol dependency presents with progressive abdominal distension. Abdominal examination reveals a
    shifting dullness. Which one of the following is the most appropriate drug to relieve this abdominal distension?

  2. Which one of the following is the investigation of choice for diagnosing the presence of stones in the gall-bladder?

  3. Which one of the following biologic agents used in the treatment of inflammatory Bowel Disease acts by inhibiting the enzyme 'Janus Kinase'?

  4. Melanosis coli, which occurs due to long term consumption of stimulant laxatives, presents as brown dis-colouration of colonic mucosa due to
    deposition of which one of the following pigments?

  5. Consider the following with regard to Gilbert Syndrome:

    I. Autosomal recessive trait of a mutation in gene for UDP- glucuronyl transferase enzyme

    II. Elevation of unconjugated bilirubin

    III. No stigmata of chronic liver disease other than jaundice

    IV. Early Liver biopsy recommended in patients with possible Gilbert Syndrome

    Which of the above are correct?

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