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Question

A 10-month-old girl presents with extensive pruritis over the face and lichenification and creases below the eyes. She has a family history of asthma and allergic rhinitis. The most likely diagnosis is

The correct answer is
Atopic dermatitis

Identifying Atopic Dermatitis in Infants

The diagnosis relies on evaluating the patient's age, symptoms, and family history.

Clinical Presentation Analysis

  • Age: 10-month-old girl, a common age for the onset of atopic dermatitis.
  • Symptoms: Extensive facial pruritis (itching) and lichenification (thickened skin from scratching) are hallmark signs. The creases below the eyes (potentially Dennie-Morgan lines) suggest chronic irritation.
  • Distribution: Facial involvement is typical in infants with atopic dermatitis.

Family History Significance

A family history of asthma and allergic rhinitis is crucial. These conditions, along with atopic dermatitis, form the "atopic triad," significantly increasing the likelihood of atopy in the patient.

Differential Diagnosis Review

  • Atopic dermatitis: Best fits the clinical picture due to infant age, pruritis, facial rash, lichenification, and strong atopic family history.
  • Allergic contact dermatitis: Less likely without a specific external trigger and typically presents differently.
  • Seborrhoeic dermatitis: Usually presents with greasy scales (cradle cap) and is less intensely pruritic or lichenified in this manner.
  • Neurodermatitis: Often a secondary result of chronic scratching, usually superimposed on an underlying condition like atopic dermatitis.

Conclusion

The combination of symptoms (pruritis, lichenification, facial rash) in an infant, coupled with a family history of asthma and allergic rhinitis, strongly points towards atopic dermatitis as the most likely diagnosis.

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Important Questions from Eczema

  1. Allergic contact dermatitis is a manifestation of:
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