UPSC CMS 2023 General Medicine and Pediatrics Paper 1 Question Paper (16-Jul-2023)

Question 1

Which of the following statements are correct for the treatment of chronic hepatitis B with pegylated interferon (PEG-IFN)? 1. PEG-IFN is poorly tolerated drug as compared to nucleoside analogues. 2. Resistance to treatment with PEG-IFN is common than nucleoside analogues. 3. PEG-IFN is not useful in patients of cirrhosis. 4. PEG-IFN is administered every week for 48 weeks. Select the correct answer using the code given below.

Accepted Answer

1, 3 and 4

Answer

1, 2 and 3

Answer

2 and 4

Answer

1 and 3 only

Question 2

Which of the following are recommended for management of tumour lysis syndrome? 1. Urinary alkalinization 2. Intravenous fluids 3. Rasburicase 4. Febuxostat Select the correct answer using the code given below.

Accepted Answer

2, 3 and 4

Answer

1, 2 and 3

Answer

1, 2 and 4

Answer

1, 3 and 4

Question 3

Focal seizures may be associated with which of the following? 1. Jacksonian march 2. Todd's paralysis 3. Epilepsia partialis continua Select the correct answer using the code given below.

Accepted Answer

1, 2 and 3

Answer

1 and 2 only

Answer

2 and 3 only

Answer

1 and 3 only

Question 4

Typical absence seizures are characterized by

Accepted Answer

abrupt 3 Hz spike-and-slow wave discharges on EEG

Answer

postictal confusion in children

Answer

multifocal structural abnormalities of brain

Answer

less responsiveness to anti-convulsants as compared to atypical absence seizures

Question 5

Which of the following are contra-indications to thrombolysis in acute ischemic stroke? 1. Recent head injury 2. Recent MI 3. Hypertension > 150/100 mm Hg 4. GI bleeding in last 3 weeks Select the correct answer using the code given below.

Accepted Answer

1, 2 and 4

Answer

1, 2 and 3

Answer

1, 3 and 4

Answer

2, 3 and 4